Scientific Notes Taken in the Himalayas

Notes on Complexity Theory Notes Taken From

I assume that most students have encountered Turing machines before. (Students who have not may want to look at Sipser’s book [3].) A Turing machine is defined by an integer k ≥ 1, a finite set of states Q, an alphabet Γ, and a transition function δ : Q×Γk → Q×Γk−1×{L, S,R}k where: • k is the number of (infinite, one-dimensional) tapes used by the machine. In the general case we have k ≥ 3 and ...

Scientific Notes

Clinical/Scientific Notes

Aicardi-Goutières syndrome (AGS) is a monogenic inflammatory disorder typically presenting in infancy as a progressive encephalopathy demonstrating phenotypic overlap in some cases with both congenital infection and systemic lupus erythematosus (SLE), with mutations in 7 genes identified. All forms are associated with a perturbation of type I interferon metabolism, with a defect in the removal,...

Clinical-scientific notes.

Neuronal distal axons have limited access to glucose, their myelin sheaths preventing direct interface with blood, and their axoplasms being at great distances from their cell bodies. Glycogen, the mammalian glucose store, is characterized by extreme branching, which allows packing 55,000 glucoses/glycogen, and maintaining solubility. In neurons, glycogen phos-phorylase, the glycogen-digesting ...

Clinical/Scientific Notes

Case report. A 12-year-old boy with multiple nevi presented with 6 months of polydipsia ( 4 L/day), polyuria, and a 40-pound weight loss that progressed over weeks to intractable headache and vomiting. The patient subsequently developed ataxia, complex partial seizures, and encephalopathy. Medical history was significant for numerous (40 to 50) benign congenital nevi ranging in diameter from 1 ...